V. Reimund, D. Farina, Y. Jiang, and O. Dössel. Reconstruction of ectopic foci using the critical point theory. In Proc. the 4th European Congress for Medical and Biomedical Engineering, vol. 22, pp. 2703-2706, 2008
The treatment of ventricular arrhythmia often requires detailed information about the location of ectopic beats. A noninvasive procedure is adopted to achieve this purpose. The aim of this work is the reconstruction of ectopic foci by using the critical point theory introduced by Greensite and Huiskamp . The reliability and adaptability of the obtained simulation results are evaluated with regard to the reconstruction error.The reconstruction of bioelectrical sources from measured body surface potentials is an ill-posed problem and requires regularization. The advantage of the presented method is to deal with a well-posed formulation of the problem. Locations of ectopic beats can be detected by the critical point theorem. Four simulated ectopic centers have been localized to evaluate the method. The influence of Gaussian noise is considered.The reconstruction depends on the effective rank of a singular value decomposition (SVD) of the multi-channel ECG matrix. Regarding lower ranks, many critical points presenting ectopic foci can be observed. For higher ranks, the detection leads more and more to a stable estimation of ectopic locations. The detected critical points are shown to be reliable approximations of the simulated ectopic foci.
Student Theses (1)
V. Reimund. Noninvasive activation time imaging of atrial and ventricular myocardium. Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT). Diplomarbeit. 2008