IBT Publications by Loewe


Journal Articles (92)

N. Pilia, S. Schuler, M. Rees, G. Moik, D. Potyagaylo, O. Dössel, and A. Loewe.
Non-invasive Localization of the Ventricular Excitation Origin Without Patient-specific Geometries Using Deep Learning.
In eprint, 2022
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J. Bender, C. Nagel, J. Fröhlich, C. Wieners, O. Dössel, and A. Loewe.
A Large-scale Virtual Patient Cohort to Study ECG Features of Interatrial Conduction Block.
In Current Directions in Biomedical Engineering, vol. 8(2) , pp. 97-100, 2022
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N. Skupien, C. Barrios Espinosa, O. Dössel, and A. Loewe.
Refining the Eikonal Model to Reproduce the Influence of Atrial Tissue Geometry on Conduction Velocity.
In Current Directions in Biomedical Engineering, vol. 8(2) , pp. 133-136, 2022
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L. Azzolin, M. Eichenlaub, C. Nagel, D. Nairn, J. Sanchez, L. Unger, O. Dössel, A. Jadidi, and A. Loewe.
Personalized ablation vs. conventional ablation strategies to terminate atrial fibrillation and prevent recurrence.
In EP Europace, pp. 1-12, 2022
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G. Luongo, G. Vacanti, V. Nitzke, D. Nairn, C. Nagel, D. Kabiri, T. P. Almeida, D. C. Soriano, M. W. Rivolta, G. A. Ng, O. Dössel, A. Luik, R. Sassi, C. Schmitt, and A. Loewe.
Hybrid machine learning to localize atrial flutter substrates using the surface 12-lead electrocardiogram.
In EP Europace, vol. 24(7) , pp. 1186-1194, 2022
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S. Schuler, M. Schaufelberger, L. R. Bear, J. A. Bergquist, M. J. M. Cluitmans, J. Coll-Font, O. N. Onak, B. Zenger, A. Loewe, R. S. MacLeod, D. H. Brooks, and O. Dossel.
Reducing Line-of-Block Artifacts in Cardiac Activation Maps Estimated Using ECG Imaging: A Comparison of Source Models and Estimation Methods.
In IEEE Transactions on Biomedical Engineering, vol. 69(6) , pp. 2041-2052, 2022
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J. Sánchez, and A. Loewe.
A Review of Healthy and Fibrotic Myocardium Microstructure Modeling and Corresponding Intracardiac Electrograms.
In Frontiers in Physiology, vol. 13, 2022
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T. Gerach, S. Appel, J. Wilczek, K. S. Golba, T. Jadczyk, and A. Loewe.
Dyssynchronous Left Ventricular Activation is Insufficient for the Breakdown of Wringing Rotation.
In Frontiers in Physiology, vol. 13(eCollection) , 2022
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T. Gerach, S. Schuler, A. Wachter, and A. Loewe.
The Impact of Standard Ablation Strategies for Atrial Fibrillation on Cardiovascular Performance in a Four-chamber Heart Model.
In arXiv, 2022
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A. Loewe, and H. Anzt.
Es ist Zeit über Forschungssoftware zu reden.
2022
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C. Nagel, M. Schaufelberger, O. Dössel, and A. Loewe.
A Bi-atrial Statistical Shape Model as a Basis to Classify Left Atrial Enlargement from Simulated and Clinical 12-Lead ECGs.
In Statistical Atlases and Computational Models of the Heart. Multi-Disease, Multi-View, and Multi-Center Right Ventricular Segmentation in Cardiac MRI Challenge, vol. 13131, pp. 38-47, 2022
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D. Nairn, M. Eichenlaub, B. Müller-Edenborn, H. Lehrmann, C. Nagel, L. Azzolin, G. Luongo, R. Figueras Ventura, B. Rubio Forcada, A. Colomer, T. Arentz, O. Dössel, A. Loewe, and A. Jadidi.
LGE-MRI for diagnosis of left atrial cardiomyopathy as identified in high-definition endocardial voltage and conduction velocity mapping.
In medRxiv, 2022
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F. Bach, J. Klar, A. Loewe, J. Sánchez, G. Seemann, Y.-L. Huang, and R. Ulrich.
The openCARP CDE - Concept for and implementation of a sustainable collaborative development environment for research software.
In Bausteine Forschungsdatenmanagement, vol. 2022(1) , pp. 64-84, 2022
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C. Nagel, C. B. Espinosa, K. Gillette, M. A. Gsell, J. Sánchez, G. Plank, O. DÖssel, and A. Loewe.
Comparison of Propagation Models and Forward Calculation Methods on Cellular, Tissue and Organ Scale Atrial Electrophysiology.
In IEEE Transactions on Biomedical Engineering(4359967) , pp. 1-12, 2022
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A. Amsaleg, J. Sánchez, R. Mikut, and A. Loewe.
Characterization of the Pace-and-Drive Capacity of the Human Sinoatrial Node: a 3D in silico Study.
In bioRxiv, 2022
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L. Azzolin, M. Eichenlaub, C. Nagel, D. Nairn, J. Sánchez, L. Unger, O. Dössel, A. Jadidi, and A. Loewe.
AugmentA: Patient-specific Augmented Atrial model Generation Tool.
In medRxiv, 2022
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D. Nairn, M. Eichenlaub, H. Lehrmann, B. Müller-Edenborn, J. Chen, T. Huang, C. Nagel, J. Sánchez, G. Luongo, T. Arentz, O. Dössel, A. Jadidi, and A. Loewe.
Spatial Correlation of Left Atrial Low Voltage Substrate in Sinus Rhythm versus Atrial Fibrillation: Identifying the Pathological Substrate Irrespective of the Rhythm.
2022
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O. Berenfeld, V. D. A. Corino, A. Loewe, J. P. Martínez, and J. F. Rodriguez Matas.
Editorial: Atrial Fibrillation: Technology for Diagnosis, Monitoring, and Treatment.
In Frontiers in Physiology, vol. 13, 2022
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G. Luongo, F. Rees, D. Nairn, M. W. Rivolta, O. Dössel, R. Sassi, C. Ahlgrim, L. Mayer, F.-J. Neumann, T. Arentz, A. Jadidi, A. Loewe, and B. Müller-Edenborn.
Machine Learning Using a Single-Lead ECG to Identify Patients With Atrial Fibrillation-Induced Heart Failure.
In Frontiers in Cardiovascular Medicine, vol. 9, 2022
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T. Zheng, L. Azzolin, J. Sánchez, O. Dössel, and A. Loewe.
An automate pipeline for generating fiber orientation and region annotation in patient specific atrial models.
In Current Directions in Biomedical Engineering, vol. 7(2) , pp. 136-139, 2021
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G. Plank, A. Loewe, A. Neic, C. Augustin, Y.-L. Huang, M. A. F. Gsell, E. Karabelas, M. Nothstein, A. J. Prassl, J. Sánchez, G. Seemann, and E. J. Vigmond.
The openCARP simulation environment for cardiac electrophysiology..
In Computer Methods and Programs in Biomedicine, vol. 208, pp. 106223, 2021
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H. Anzt, and A. Loewe.
Forschungssoftware – Nachhaltige Entwicklung und Bereitstellung.
In Forschung & Lehre, vol. 28(5) , pp. 380-381, 2021
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C. Nagel, G. Luongo, L. Azzolin, S. Schuler, O. Dössel, and A. Loewe.
Non-Invasive and Quantitative Estimation of Left Atrial Fibrosis Based on P Waves of the 12-Lead ECG-A Large-Scale Computational Study Covering Anatomical Variability..
In Journal of Clinical Medicine, vol. 10(8) , 2021
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L. A. Unger, L. Azzolin, M. Nothstein, J. Sánchez, A. Luik, G. Seemann, S. Yeshwant, T. Oesterlein, O. Dössel, C. Schmitt, P. Spector, and A. Loewe.
Cycle length statistics during human atrial fibrillation reveal refractory properties of the underlying substrate: a combined in silico and clinical test of concept study..
In EP Europace, vol. 23(Supplement_1) , pp. i133-i142, 2021
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G. Luongo, S. Schuler, A. Luik, T. P. Almeida, D. C. Soriano, O. Dossel, and A. Loewe.
Non-Invasive Characterization of Atrial Flutter Mechanisms Using Recurrence Quantification Analysis on the ECG: A Computational Study.
In IEEE Transactions on Biomedical Engineering, vol. 68(3) , pp. 914-925, 2021
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Y. Lutz, T. Meiner, L. Krames, G. Cattaneo, S. Meckel, O. Dossel, and A. Loewe.
Selective Brain Hypothermia for Ischemic MCA-M1 Stroke: Influence of Cerebral Arterial Circulation in a 3D Brain Temperature Model.
In IEEE Transactions on Biomedical Engineering, vol. 68(2) , pp. 404-415, 2021
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E. Kovacheva, L. Thämer, T. Fritz, G. Seemann, M. Ochs, O. Dössel, and A. Loewe.
Estimating cardiac active tension from wall motion—An inverse problem of cardiac biomechanics.
In International Journal for Numerical Methods in Biomedical Engineering, vol. 37(12) , pp. e3448, 2021
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G. Luongo, L. Azzolin, S. Schuler, M. W. Rivolta, T. P. Almeida, J. P. Martínez, D. C. Soriano, A. Luik, B. Müller-Edenborn, A. Jadidi, O. Dössel, R. Sassi, P. Laguna, and A. Loewe.
Machine learning enables noninvasive prediction of atrial fibrillation driver location and acute pulmonary vein ablation success using the 12-lead ECG.
In Cardiovascular Digital Health Journal, vol. 2(2) , pp. 126-136, 2021
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E. Kovacheva, T. Gerach, S. Schuler, M. Ochs, O. Dössel, and A. Loewe.
Causes of altered ventricular mechanics in hypertrophic cardiomyopathy: an in-silico study.
In BioMedical Engineering OnLine, vol. 20(1) , pp. 69, 2021
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M. Viceconti, L. Emili, P. Afshari, E. Courcelles, C. Curreli, N. Famaey, L. Geris, M. Horner, M. C. Jori, A. Kulesza, A. Loewe, M. Neidlin, M. Reiterer, C. F. Rousseau, G. Russo, S. J. Sonntag, E. M. Voisin, and F. Pappalardo.
Possible Contexts of Use for In Silico Trials Methodologies: A Consensus-Based Review.
In IEEE Journal of Biomedical and Health Informatics, vol. 25(10) , pp. 3977-3982, 2021
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L. Azzolin, S. Schuler, O. Dössel, and A. Loewe.
A Reproducible Protocol to Assess Arrhythmia Vulnerability : Pacing at the End of the Effective Refractory Period..
In Frontiers in Physiology, vol. 12, pp. 656411, 2021
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M. Nothstein, A. Luik, A. Jadidi, J. Sánchez, L. A. Unger, E. M. Wülfers, O. Dössel, G. Seemann, C. Schmitt, and A. Loewe.
CVAR-Seg: An Automated Signal Segmentation Pipeline for Conduction Velocity and Amplitude Restitution..
In Frontiers in Physiology, vol. 12, pp. 673047, 2021
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T. Gerach, S. Schuler, J. Fröhlich, L. Lindner, E. Kovacheva, R. Moss, E. M. Wülfers, G. Seemann, C. Wieners, and A. Loewe.
Electro-Mechanical Whole-Heart Digital Twins: A Fully Coupled Multi-Physics Approach.
In Mathematics, vol. 9(11) , pp. 1247, 2021
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J. Sánchez, G. Luongo, M. Nothstein, L. A. Unger, J. Saiz, B. Trenor, A. Luik, O. Dössel, and A. Loewe.
Using Machine Learning to Characterize Atrial Fibrotic Substrate From Intracardiac Signals With a Hybrid in silico and in vivo Dataset.
In Frontiers in Physiology, vol. 12, pp. 699291, 2021
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M. Eichenlaub, B. Mueller-Edenborn, H. Lehrmann, J. Minners, D. Nairn, A. Loewe, J. Allgeier, N. Jander, M. Allgeier, P. Ruile, M. Hein, F. Rees, D. Trenk, R. Weber, F.-J. Neumann, T. Arentz, and A. Jadidi.
Non-invasive body surface electrocardiographic imaging for diagnosis of atrial cardiomyopathy.
In EP Europace, vol. 23(12) , pp. 2010-2019, 2021
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S. Schuler, N. Pilia, D. Potyagaylo, and A. Loewe.
Cobiveco: Consistent biventricular coordinates for precise and intuitive description of position in the heart – with MATLAB implementation.
In Medical Image Analysis, vol. 74, pp. 102247, 2021
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R. Moss, E. M. Wülfers, S. Schuler, A. Loewe, and G. Seemann.
A Fully-Coupled Electro-Mechanical Whole-Heart Computational Model: Influence of Cardiac Contraction on the ECG.
In Frontiers in Physiology, vol. 12, 2021
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M. Vila, M. W. Rivolta, G. Luongo, L. A. Unger, A. Luik, L. Gigli, F. Lombardi, A. Loewe, and R. Sassi.
Atrial Flutter Mechanism Detection Using Directed Network Mapping.
In Frontiers in Physiology, vol. 12, 2021
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J. Brenneisen, A. Daub, T. Gerach, E. Kovacheva, L. Huetter, B. Frohnapfel, O. Dössel, and A. Loewe.
Sequential Coupling Shows Minor Effects of Fluid Dynamics on Myocardial Deformation in a Realistic Whole-Heart Model..
In Frontiers in cardiovascular medicine, vol. 8, pp. 768548, 2021
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N. Pilia, C. Nagel, G. Lenis, S. Becker, O. Dössel, and A. Loewe.
ECGdeli - An open source ECG delineation toolbox for MATLAB.
In SoftwareX, vol. 13, pp. 100639, 2021
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O. Dössel, G. Luongo, C. Nagel, and A. Loewe.
Computer Modeling of the Heart for ECG Interpretation—A Review.
In Hearts, vol. 2(3) , pp. 350-368, 2021
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C. Nagel, S. Schuler, O. Dössel, and A. Loewe.
A bi-atrial statistical shape model for large-scale in silico studies of human atria: model development and application to ECG simulations.
In Medical Image Analysis, vol. 74, pp. 102210, 2021
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J. Sánchez, B. Trenor, J. Saiz, O. Dössel, and A. Loewe.
Fibrotic Remodeling during Persistent Atrial Fibrillation: In Silico Investigation of the Role of Calcium for Human Atrial Myofibroblast Electrophysiology.
In Cells, vol. 10(11) , pp. 2852, 2021
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N. Pilia, S. Severi, J. G. Raimann, S. Genovesi, O. Dössel, P. Kotanko, C. Corsi, and A. Loewe.
Quantification and classification of potassium and calcium disorders with the electrocardiogram: What do clinical studies, modeling, and reconstruction tell us?.
In APL Bioengineering, vol. 4(4) , pp. 041501, 2020
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A. Loewe.
Ein digitales Herz.
In Spektrum der Wissenschaft, vol. 20(10) , pp. 44-48, 2020
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S. Pollnow, G. Schwaderlapp, A. Loewe, and O. Dössel.
Monitoring the dynamics of acute radiofrequency ablation lesion formation in thin-walled atria – a simultaneous optical and electrical mapping study.
In Biomedical Engineering / Biomedizinische Technik, vol. 65(3) , pp. 327-341, 2020
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Z. Kohajda, A. Loewe, N. Tóth, A. Varró, and N. Nagy.
The Cardiac Pacemaker Story-Fundamental Role of the Na/Ca Exchanger in Spontaneous Automaticity..
In Frontiers in Pharmacology, vol. 11, pp. 516, 2020
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F. Wiedmann, C. Beyersdorf, X. Zhou, A. Büscher, M. Kraft, J. Nietfeld, T. P. Walz, L. A. Unger, A. Loewe, B. Schmack, A. Ruhparwar, M. Karck, D. Thomas, M. Borggrefe, G. Seemann, H. A. Katus, and C. Schmidt.
Pharmacologic TWIK‐Related Acid‐Sensitive K+ Channel (TASK‐1) Potassium Channel Inhibitor A293 Facilitates Acute Cardioversion of Paroxysmal Atrial Fibrillation in a Porcine Large Animal Model.
In Journal of the American Heart Association, vol. 9(10) , 2020
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A. Jadidi, M. Nothstein, J. Chen, H. Lehrmann, O. Dössel, J. Allgeier, D. Trenk, F.-J. Neumann, A. Loewe, B. Müller-Edenborn, and T. Arentz.
Specific Electrogram Characteristics Identify the Extra-Pulmonary Vein Arrhythmogenic Sources of Persistent Atrial Fibrillation – Characterization of the Arrhythmogenic Electrogram Patterns During Atrial Fibrillation and Sinus Rhythm.
In Scientific Reports, vol. 10(1) , pp. 9147, 2020
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D. Nairn, H. Lehrmann, B. Müller-Edenborn, S. Schuler, T. Arentz, O. Dössel, A. Jadidi, and A. Loewe.
Comparison of Unipolar and Bipolar Voltage Mapping for Localization of Left Atrial Arrhythmogenic Substrate in Patients With Atrial Fibrillation.
In Frontiers in Physiology, vol. 11, 2020
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M. Lohrer, and A. Loewe.
Herzsimulator 1.0.
In dotnetpro, vol. 2020(1) , pp. 13-19, 2020
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Y. Lutz, R. Daschner, L. Krames, A. Loewe, G. Cattaneo, S. Meckel, and O. Dössel.
Modeling selective therapeutic hypothermia in case of acute ischemic stroke using a 1D hemodynamics model and a simplified brain geometry..
In Mathematical biosciences and engineering : MBE, vol. 17(2) , pp. 1147-1167, 2020
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Z. Kohajda, N. Tóth, J. Szlovák, A. Loewe, G. Bitay, P. Gazdag, J. Prorok, N. Jost, J. Levijoki, P. Pollesello, J. G. Papp, A. Varró, and N. Nagy.
Novel Na/Ca Exchanger Inhibitor ORM-10962 Supports Coupled Function of Funny-Current and Na/Ca Exchanger in Pacemaking of Rabbit Sinus Node Tissue..
In Frontiers in Pharmacology, vol. 10, pp. 1632, 2020
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D. Frisch, T. G. Oesterlein, L. A. Unger, G. Lenis, R. Wakili, C. Schmitt, A. Luik, O. Doessel, and A. Loewe.
Mapping and Removing the Ventricular Far Field Component in Unipolar Atrial Electrograms..
In IEEE Transactions on Biomedical Engineering, vol. 67(10) , pp. 2905-2915, 2020
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N. Pilia, C. Corsi, S. Severi, O. Dössel, and A. Loewe.
Reconstruction of Potassium Concentrations with the ECG on Imbalanced Datasets.
2020
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C. Nagel, N. Pilia, A. Loewe, and O. Dössel.
Quantification of Interpatient 12-lead ECG Variabilities within a Healthy Cohort.
In Current Directions in Biomedical Engineering, vol. 6(3) , pp. 493-496, 2020
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M. Nothstein, A. Luik, A. Jadidi, E. M. Wülfers, O. Dössel, G. Seemann, C. Schmitt, and A. Loewe.
Investigating the correlation of local rate dependency of atrial conduction velocity and voltage.
2019
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Y. Lutz, A. Loewe, S. Meckel, O. Dössel, and G. Cattaneo.
Combined local hypothermia and recanalization therapy for acute ischemic stroke: Estimation of brain and systemic temperature using an energetic numerical model..
In Journal of Thermal Biology, vol. 84, pp. 316-322, 2019
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A. Loewe, E. Poremba, T. Oesterlein, A. Luik, C. Schmitt, G. Seemann, and O. Dössel.
Patient-Specific Identification of Atrial Flutter Vulnerability–A Computational Approach to Reveal Latent Reentry Pathways.
In Frontiers in Physiology, vol. 9(Article 1910) , 2019
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A. Loewe, Y. Lutz, D. Nairn, A. Fabbri, N. Nagy, N. Toth, X. Ye, D. H. Fuertinger, S. Genovesi, P. Kotanko, J. G. Raimann, and S. Severi.
Hypocalcemia-Induced Slowing of Human Sinus Node Pacemaking.
In Biophysical Journal, vol. 117(12) , pp. 2244-2254, 2019
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M. Hernández Mesa, N. Pilia, O. Dössel, and A. Loewe.
Influence of ECG Lead Reduction Techniques for Extracellular Potassium and Calcium Concentration Estimation.
In Current Directions in Biomedical Engineering, vol. 5(1) , pp. 69-72, 2019
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A. Loewe, Y. Lutz, N. Nagy, A. Fabbri, C. Schweda, A. Varró, and S. Severi.
Inter-Species Differences in the Response of Sinus Node Cellular Pacemaking to Changes of Extracellular Calcium.
2019
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Y. Wang, Z. Xiong, A. Nalar, B. J. Hansen, S. Kharche, G. Seemann, A. Loewe, V. V. Fedorov, and J. Zhao.
A robust computational framework for estimating 3D Bi-Atrial chamber wall thickness.
In Computers in Biology and Medicine, vol. 114, pp. 103444, 2019
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S. Hallensleben, and A. Loewe.
Wie wirken Arzt und digitale Technik im Jahr 2035 zusammen?.
2019
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J. Sánchez, M. Nothstein, L. Unger, J. Saiz, B. Trénor, O. Dössel, and A. Loewe.
Influence of Fibrotic Tissue Arrangement on Intracardiac Electrograms During Persistent Atrial Fibrillation.
2019
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R. Andlauer, G. Seemann, L. Baron, O. Dössel, P. Kohl, P. Platonov, and A. Loewe.
Influence of left atrial size on P-wave morphology: differential effects of dilation and hypertrophy.
2018
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S. Pollnow, N. Pilia, G. Schwaderlapp, A. Loewe, O. Dössel, and G. Lenis.
An adaptive spatio-temporal Gaussian filter for processing cardiac optical mapping data.
In Computers in Biology and Medicine, vol. 102, pp. 267-277, 2018
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A. Loewe, E. M. Wülfers, and G. Seemann.
Cardiac ischemia-insights from computational models..
In Herzschrittmachertherapie & Elektrophysiologie, vol. 29(1) , pp. 48-56, 2018
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T. G. Oesterlein, A. Loewe, G. Lenis, A. Luik, C. Schmitt, and O. Doessel.
Automatic Identification of Reentry Mechanisms and Critical Sites during Atrial Tachycardia by Analyzing Areas of Activity..
In IEEE Transactions on Bio-Medical Engineering, vol. 65(10) , pp. 2334-2344, 2018
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B. Verma, T. Oesterlein, A. Loewe, A. Luik, C. Schmitt, and O. Dössel.
Regional conduction velocity calculation from clinical multichannel electrograms in human atria.
In Computers in Biology and Medicine, vol. 92, pp. 188-196, 2018
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H. Lehrmann, A. S. Jadidi, J. Minners, J. Chen, B. Müller-Edenborn, R. Weber, O. Dössel, T. Arentz, and A. Loewe.
Novel Electrocardiographic Criteria for Real-Time Assessment of Anterior Mitral Line Block.
In JACC: Clinical Electrophysiology, vol. 4(7) , pp. 920-932, 2018
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M. Alessandrini, M. Valinoti, L. Unger, T. Oesterlein, O. Dössel, C. Corsi, A. Loewe, and S. Severi.
A Computational Framework to Benchmark Basket Catheter Guided Ablation in Atrial Fibrillation.
In Frontiers in Physiology, vol. 9, pp. 1251, 2018
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M. Hernández Mesa, N. Pilia, O. Dössel, S. Severi, and A. Loewe.
Effects of Serum Calcium Changes on the Cardiac Action Potential and the ECG in a Computational Model.
In Current Directions in Biomedical Engineering, vol. 4(1) , pp. 251-254, 2018
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A. Loewe, M. Hernandez Mesa, N. Pilia, S. Severi, and O. Dössel.
A heterogeneous formulation of the Himeno et al. human ventricular myocyte model for simulation of Body Surface ECGs.
In Computing in Cardiology, vol. 45, 2018
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O. Dössel, and A. Loewe.
Computerized modeling of the human heart.
In Zeitschrift für Medizinische Physik, vol. 27(3) , pp. 167-169, 2017
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W. Kahlmann, E. Poremba, D. Potyagaylo, O. Dössel, and A. Loewe.
Modelling of patient-specific Purkinje activation based on measured ECGs.
In Current Directions in Biomedical Engineering, vol. 3(2) , pp. 171-174, 2017
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G. Lenis, N. Pilia, A. Loewe, W. H. W. Schulze, and O. Dössel.
Comparison of Baseline Wander Removal Techniques considering the Preservation of ST Changes in the Ischemic ECG: A Simulation Study.
In Computational and Mathematical Methods in Medicine, vol. 2017, pp. 9295029, 2017
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A. Loewe, and O. Dössel.
Commentary: Virtual In-Silico Modeling Guided Catheter Ablation Predicts Effective Linear Ablation Lesion Set for Longstanding Persistent Atrial Fibrillation: Multicenter Prospective Randomized Study.
In Frontiers in Physiology, vol. 8, pp. 1113, 2017
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S. Pollnow, J. Greiner, T. Oesterlein, E. M. Wülfers, A. Loewe, and O. Dössel.
Mini Electrodes on Ablation Catheters: Valuable Addition or Redundant Information? Insights from a Computational Study.
In Computational and Mathematical Methods in Medicine, vol. 2017(Article ID 168629) , pp. 13, 2017
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O. Dössel, G. Lenis, A. Loewe, M. Rottmann, G. Seemann, and T. Oesterlein.
Model Assisted Biosignal Analysis of Atrial Electrograms.
In Technisches Messen, vol. 83(2) , pp. 102-111, 2016
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A. Loewe, M. W. Krueger, F. Holmqvist, O. Dössel, G. Seemann, and P. G. Platonov.
Influence of the earliest right atrial activation site and its proximity to interatrial connections on P-wave morphology.
In Europace, vol. 18(suppl 4) , pp. iv35-iv43, 2016
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A. Loewe, M. Wilhelms, J. Schmid, M. J. Krause, F. Fischer, D. Thomas, E. P. Scholz, O. Dössel, and G. Seemann.
Parameter estimation of ion current formulations requires hybrid optimization approach to be both accurate and reliable.
In Frontiers in Bioengineering and Biotechnology, vol. 3, pp. 209, 2016
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T. Oesterlein, D. Frisch, A. Loewe, O. Dössel, G. Seemann, C. Schmitt, and A. Luik.
Basket-Type Catheters: Diagnostic Pitfalls caused by Deformation and Limited Coverage.
In BioMed Research International, vol. Article ID 5340574, pp. 1-13, 2016
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D. Potyagaylo, A. Loewe, P. van Dam, and O. Dössel.
ECG imaging of focal atrial excitation: Evaluation in a realistic simulation setup.
In Computing in Cardiology, vol. 43, pp. 113-116, 2016
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A. Loewe, M. W. Krueger, P. G. Platonov, F. Holmqvist, O. Dössel, and G. Seemann.
Left and Right Atrial Contribution to the P-wave in Realistic Computational Models.
In Functional Imaging and Modeling of the Heart, vol. 9126(9126) , pp. 439-447, 2015
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A. Wachter, A. Loewe, M. W. Krueger, O. Dössel, and G. Seemann.
Mesh structure-independent modeling of patient-specific atrial fiber orientation.
In Current Directions in Biomedical Engineering, vol. 1(1) , pp. 409-412, 2015
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A. Loewe, Y. Lutz, M. Wilhelms, D. Sinnecker, P. Barthel, E. P. Scholz, O. Dössel, G. Schmidt, and G. Seemann.
In-silico assessment of the dynamic effects of amiodarone and dronedarone on human atrial patho-electrophysiology..
In Europace, vol. 16(S4) , pp. iv30-iv38, 2014
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A. Loewe, W. H. W. Schulze, Y. Jiang, M. Wilhelms, A. Luik, O. Dössel, and G. Seemann.
ECG-Based Detection of Early Myocardial Ischemia in a Computational Model: Impact of Additional Electrodes, Optimal Placement, and a New Feature for ST Deviation.
In BioMed Research International Article, vol. 2015, pp. 530352, 2014
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A. Loewe, M. Wilhelms, F. Fischer, E. P. Scholz, O. Dössel, and G. Seemann.
Arrhythmic potency of human ether-a-go-go-related gene mutations L532P and N588K in a computational model of human atrial myocytes.
In Europace, vol. 16(3) , pp. 435-443, 2014
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F. Appel, and A. Loewe.
Forschungssoftware – Nachhaltige Entwicklung und Unterstützung.
  PDF    
F. Appel, and A. Loewe.
Research Software–Sustainable Development and Support.
In IAMO Policy Briefs, vol. 42,
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Books (1)

C. Wieners, O. Dössel, A. Loewe, B. Frohnapfel, and V. Heuveline.
Book of Abstracts - Workshop on Cardiac Modeling. - Towards an integrated numerical heart model, Coupling the relevant physics the right way.
April 15-17 2019, Bad Herrenalb, Germany. 2019.
  PDF  

Conference Contributions (109)

J. Brenneisen, D. Müller, A. Stroh, B. Frohnapfel, O. Dössel, and A. Loewe.
Cardiac fluid dynamics based on immersed boundary method for application in hypertrophic cardiomyopathy.
In 7th International Conference on Computational & Mathematical Biomedical Engineering - CMBE2021, pp. 439 - 442, 2022
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L. Azzolin, C. Nagel, D. Nairn, J. Sanchez, T. Zheng, M. Eichenlaub, A. Jadidi, O. Doessel, and A. Loewe.
Automated Framework for the Augmentation of Missing Anatomical Structures and Generation of Personalized Atrial Models from Clinical Data.
In Computing in Cardiology Conference (CinC), vol. 48, 2021
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J. Brenneisen, S. Schuler, E. Kovacheva, T. Gerach, O. Dössel, and A. Loewe.
Influence of Geometrical Properties for the Calculation of a Pressure-Free Whole Heart Geometry.
In 14th WCCM-ECCOMAS Congress 2020, pp. 1-9, 2021
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D. Nairn, C. Nagel, B. Mueller-Edenborn, H. Lehrmann, A. Jadidi, and A. Loewe.
Spatial and quantitative assessment of the correlation between sinus rhythm and atrial fibrillation voltage mapping to identify low voltage substrate in persistent atrial fibrillation.
In EP Europace, vol. 23(Supplement_3) , 2021
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J. Brenneisen, C. Wentzel, F. Karwan, O. Dössel, and A. Loewe.
Fluid dynamics in the human heart: Altered vortex formation and wash-out in mitral regurgitation simulations.
In Current Directions in Biomedical Engineering, vol. 7(2) , pp. 199-202, 2021
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S. Appel, T. Gerach, O. Dössel, and A. Loewe.
Adaptation of the Calcium-dependent Tension Development in Ventricular Cardiomyocytes.
In Current Directions in Biomedical Engineering, vol. 7(2) , pp. 251-254, 2021
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C. Nagel, O. Dössel, and A. Loewe.
Sensitivity and Generalization of a Neural Network for Estimating Left Atrial Fibrotic Volume Fractions from the 12-lead ECG.
In Current Directions in Biomedical Engineering, vol. 7(2) , pp. 307-310, 2021
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L. Schicketanz, L. A. Unger, J. Sánchez, O. Dössel, and A. Loewe.
Separating atrial near fields and atrial far fields in simulated intra-atrial electrograms.
In Current Directions in Biomedical Engineering, vol. 7(2) , pp. 175-178, 2021
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H. Welle, C. Nagel, A. Loewe, R. Mikut, and O. Dössel.
Classification of Bundle Branch Blocks with QRS Templates Extracted from 12-lead ECGs.
In Current Directions in Biomedical Engineering, vol. 7(2) , pp. 582-585, 2021
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G. Luongo, S. Schuler, M. W. Rivolta, O. Dössel, R. Sassi, and A. Loewe.
Semi-Supervised vs. Supervised Learning for Discriminating Atrial Flutter Mechanisms Using the 12-lead ECG.
In Computing in Cardiology Conference (CinC), vol. 48, 2021
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J. Brenneisen, A. Daub, E. Kovacheva, T. Gerach, L. Hütter, B. Frohnapfel, O. Dössel, and A. Loewe.
A sequential coupling approach for fluid-structure interaction in a patient specific whole heart geometry.
In iHEART Congress – Modelling the Cardiac Function, 2021
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O. Dössel, C. Schmitt, L. Unger, A. Loewe, and A. Luik.
Atrial Signals 2021. Book of Abstracts.
In 4th Atrial Signals Proceedings, 2021
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M. Vila, M. W. Rivolta, G. Luongo, A. Loewe, and R. Sassi.
Directed Network Mapping Hints the Ablation Strategy for Atrial Flutter: a Proof of Concept.
In 4th Atrial Signals Proceedings, pp. 16, 2021
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P. T. Cervera, J. Sanchez, O. Dössel, and A. Loewe.
Source Estimation in Cardiac Fibrotic Substrate from Intracardiac Signals.
In 4th Atrial Signals Proceedings, pp. 14, 2021
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P. Martinez Diaz, L. Azzolin, J. P. Sanchez A., C. Nagel, O. Dössel, and A. Loewe.
Influence of the Right Atrium for Arrhythmia Vulnerability: Geometry Inference Using a Statistical Shape Model.
In 4th Atrial Signals Proceedings, pp. 9, 2021
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C. Barrios E., N. Skupien, G. Kachel, O. Dössel, and A. Loewe.
Influence of Wave-Front and Atrial Tissue Properties on Eikonal Model Simulations.
In 4th Atrial Signals Proceedings, pp. 1, 2021
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J. Sánchez, T. P. Almeida, D. C. Soriano, G. A. Ng, B. Trénor, J. Saiz, A. Luik, O. Dössel, and A. Loewe.
Directed Graph Information Flow Mapping for Characterizing Cardiac Electrical Propagation from Unannotated Unipolar Electrograms.
In HeartRhythm, vol. 18(8) , pp. S371, 2021
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J. Brenneisen, E. Kovacheva, T. Gerach, A. Daub, L. Hütter, B. Frohnapfel, O. Dössel, and A. Loewe.
Characterization of the Fluid Dynamic Pressure Field in the Human Heart as a Basis for Coupled Fluid-Structure Simulations.
In BMT 2020, vol. Poster Session, pp. 259, 2020
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A. Loewe, Y. Lutz, D. Nairn, A. Fabbri, N. Nagy, N. Toth, X. Ye, D. Fuertinger, S. Genovesi, M. Kuhlmann, P. Kotanko, J. Raimann, and S. Severi.
Can Hypocalcaemia Cause Severe Sinus Bradycardia and Asystole in Dialysis Patients?.
In Clinical research in cardiology: Official journal of the German Cardiac Society, vol. 109(Suppl 1) , pp. 1, 2020
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G. Luongo, S. Schuler, M. W. Rivolta, O. Dössel, R. Sassi, and A. Loewe.
Automatic classification of 20 different types of atrial tachycardia using 12-lead ECG signals.
In EP Europace, vol. 22(Supplement_1) , 2020
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T. Gerach, S. Schuler, E. Kovacheva, O. Doessel, and A. Loewe.
Consequences of Using an Orthotropic Stress Tensor for Left Ventricular Systole.
In 2020 Computing in Cardiology Conference (CinC), vol. 47, 2020
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J. Sánchez, M. Nothstein, A. Neic, Y.-L. Huang, A. J. Prassl, J. Klar, R. Ulrich, F. Bach, P. Zschumme, M. Selzer, G. Plank, E. Vigmond, G. Seemann, and A. Loewe.
openCARP: An Open Sustainable Framework for In-Silico Cardiac Electrophysiology Research.
In Computing in Cardiology, vol. 47, 2020
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T. Paggi de Almeida, M. Nothstein, X. Li, M. Masè, F. Ravelli, D. C. Soriano, A. S. Bezerra, F. S. Schlindwein, T. Yoneyama, O. Dössel, G. André Ng, and A. Loewe.
Phase Singularities in Cardiac Patch Model with Non-conductive Fibrotic Area during Atrial Fibrillation.
In Computing in Cardiology Conference (CinC), vol. 47, 2020
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D. Nairn, D. Hunyar, J. Sánchez, O. Doessel, and A. Loewe.
Impact of Electrode Size on Electrogram Voltage in Healthy and Diseased Tissue.
In Computing in Cardiology Conference (CinC), vol. 47, 2020
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J. Elliott, O. Doessel, A. Loewe, L. Mainardi, V. Corino, and J. F Rodriguez Matas.
An In-silico Study Into The Impact of Electrophysiological Variability at the Cellular Level on the Reentry Patterns in Atrial Fibrillation.
In Computing in Cardiology Conference (CinC), vol. 47, 2020
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G. Luongo, L. Azzolin, M. W. Rivolta, R. Sassi, J. P. Martinez, P. Laguna, O. Doessel, and A. Loewe.
Non-invasive identification of atrial fibrillation driver location using the 12-lead ECG: pulmonary vein rotors vs. other locations.
In EMBC 20, 2020
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E. Kovacheva, L. Baron, S. Schuler, T. Gerach, O. Dössel, and A. Loewe.
Optimization Framework to Identify Constitutive Law Parameters of the Human Heart.
In Current Directions in Biomedical Engineering, vol. 6(3) , pp. 95-98, 2020
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A. Müller, E. Kovacheva, M. Fritz, O. Dössel, and A. Loewe.
Validating a Numerical Simulation of Human Heart Motion Using Clinical Data.
In Current Directions in Biomedical Engineering, vol. 6(3) , pp. 547-550, 2020
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L. Azzolin, G. Luongo, S. Rocher, J. Saiz, O. Doessel, and A. Loewe.
Influence of Gradient and Smoothness of Atrial Wall Thickness on Initiation and Maintenance of Atrial Fibrillation.
In Computing in Cardiology Conference (CinC), 2020
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G. Luongo, L. Azzolin, M. W. Rivolta, T. P. Almeida, J. P. Martinez, D. C. Soriano, O. Dössel, R. Sassi, P. Laguna, and A. Loewe.
Machine Learning to Find Areas of Rotors Sustaining Atrial Fibrillation From the ECG.
In Computing in Cardiology, 2020
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G. Luongo, S. Schuler, M. W. Rivolta, O. Dössel, R. Sassi, and A. Loewe.
Automatic ECG-based Discrimination of 20 Atrial Flutter Mechanisms: Influence of Atrial and Torso Geometries.
In Computing in Cardiology, 2020
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A. Loewe, G. Seemann, E. M. Wülfers, Y.-L. Huang, J. Sanchez, F. Bach, R. Ulrich, and M. Selzer.
SuLMaSS - Sustainable Lifecycle Management for Scientific Software.
In E-Science-Tage 2019: Data to Knowledge, 2019
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T. Fritz, E. Kovacheva, G. Seemann, O. Dössel, and A. Loewe.
The inverse problem of cardiac mechanics - estimation of cardiac active stress from endocardial motion tracking.
In Computational & Mathematical Biomedical Engineering Proceedings, vol. 1, pp. 91-95, 2019
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M. Nothstein, A. Luik, A. Jadidi, E. M. Wülfers, O. Dössel, G. Seemann, C. Schmitt, and A. Loewe.
Rate Dependency of Global and Local Atrial Conduction Velocity based on Intracardiac Signals.
In Deutsche Gesellschaft für Kardiologie 85. Jahrestagung Mannheim, 2019
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A. Loewe, Y. Lutz, A. Fabbri, and S. Severi.
Sinus Bradycardia Due to Electrolyte Changes as a Potential Pathomechanism of Sudden Cardiac Death in Hemodialysis Patients.
In Biophysical Journal, vol. 116(3 suppl1) , pp. 231A, 2019
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D. Nairn, X. Ye, D. H. Fuertinger, P. Kotanko, A. Loewe, and J. Raimann.
FP616 Low Serum Calcium is Correlated with Lower Heart Rate in Elderly Dialysis Patients.
In Nephrology Dialysis Transplantation, vol. 34(S1) , 2019
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L. Krames, R. Daschner, Y. Lutz, A. Loewe, O. Dössel, and G. Cattaneo.
Modeling of the Human Cerebral Collateral Circulation: Evaluation of the Impact on the Cerebral Perfusion in Case of Ischemic Stroke.
In Current Directions in Biomedical Engineering, vol. 5(1) , pp. 533-536, 2019
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R. Daschner, L. Krames, Y. Lutz, A. Loewe, O. Dössel, and G. Cattaneo.
Generation of a Simplified Brain Geometry for the Calculation of Local Cerebral Temperature using a 1D Hemodynamic Model.
In Current Directions in Biomedical Engineering, vol. 5(1) , pp. 529-532, 2019
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A. Loewe, Y. Lutz, N. Nagy, A. Fabbri, C. Schweda, A. Varro, and S. Severi.
Inter-Species Differences in the Response of Sinus Node Cellular Pacemaking to Changes of Extracellular Calcium.
In 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 1875-1878, 2019
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Y. Lutz, R. Daschner, L. Krames, A. Loewe, O. Dössel, and G. Cattaneo.
Estimating Local Therapeutic Hypothermia in Case of Ischemic Stroke Using a 1D Hemodynamics Model and an Energetic Temperature Model.
In 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 3983-3986, 2019
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N. Pilia, M. Hernandez Mesa, O. Dössel, and A. Loewe.
ECG-based Estimation of Potassium and Calcium Concentrations: Proof of Concept with Simulated Data.
In IEEE Engineering in Medicine and Biology (EMBC), pp. 2610-2613, 2019
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D. Nairn, X. Ye, D. H. Fuertinger, P. Kotanko, A. Loewe, and J. G. Raimann.
Hypocalcemia-Induced Bradycardia Is More Pronounced in Male Hemodialysis Patients.
In Kidney Week 2019, vol. 30(AS) , pp. 542-543, 2019
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T. P. Almeida, L. A. Unger, D. C. Soriano, X. Li, O. Dössel, T. Yoneyama, and A. Loewe.
Recurrence Quantification Analysis for Investigating Atrial Fibrillation Dynamics in a Heterogeneous Simulation Setup*.
In 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 2277-2280, 2019
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L. A. Unger, T. G. Oesterlein, A. Loewe, and O. Dössel.
Noise quantification and noise reduction for unipolar and bipolar electrograms.
In Computing in Cardiology (CinC), vol. 46, 2019
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J. Elliott, O. Dössel, A. Loewe, L. Mainardi, V. Corino, and J. F. Rodriquez Matas.
An In-Silico Study of the Effects of Conductance Variation on the Regionally Based Action Potential Morphology.
In Computing in Cardiology (CinC), vol. 46, 2019
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G. Luongo, S. Schuler, O. Dössel, and A. Loewe.
12-Lead ECG Feature Identification to Discriminate Different Types of Atrial Flutter.
In 41 Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019
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G. Luongo, S. Schuler, T. P. Almeida, D. C. Soriano, O. Dössel, and A. Loewe.
Discrimination of Atrial Flutter on Simulated 12-Lead-ECG Signals by Applying Biosignal Processing.
In Gordon Research Conference - Cardiac Arrhythmia Mechanisms, 2019
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L. Azzolin, O. Dössel, and A. Loewe.
Influence of the protocol used to induce arrhythmia on atrial fibrillation vulnerability.
In 41 Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019
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T. Gerach, D. Weiß, O. Dössel, and A. Loewe.
Observation guided systematic reduction of a detailed human ventricular cell model.
In Computing in Cardiology (CinC), vol. 46, 2019
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D. Nairn, H. Lehrmann, A. Jadidi, O. Dössel, and A. Loewe.
Comparison of Voltage Map Calculation Methods using Non-Fractionated EGM Signals in a Persistent AF Patient.
In Computing in Cardiology (CinC), vol. 46, 2019
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E. Kovacheva, S. Schuler, T. Gerach, O. Dössel, and A. Loewe.
A Method for Pressure-Volume-Based Parameter Identification for a Passive Constitutive Model of Myocardium.
In RISM Congress: iHEART - Modelling the Cardiac Function, 2019
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L. Azzolin, J. Sanchez, S. Schuler, O. Dössel, and A. Loewe.
Initiation and maintenance of re-entrant cardiac propagation: a computational vulnerability study.
In Gordon Research Conference - Cardiac Arrhythmia Mechanisms, 2019
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M. Nothstein, A. Luik, A. Jadidi, O. Dössel, C. Schmitt, G. Seemann, and A. Loewe.
Automated Stimulus Artefact Removal for the Clinical S1-S2 Pacing Protocol.
In Engineering in Medicine and Biology Society (EMBC), 2019 Annual International Conference of the IEEE, 2019
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S. Schuler, A. Loewe, and O. Dössel.
Forcing Transmembrane Voltages to Decrease Slowly: A Temporal Regularization for ECG Imaging.
In Computing in Cardiology, vol. 45, 2018
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O. Dössel, T. Oesterlein, L. Unger, A. Loewe, C. Schmitt, and A. Luik.
Spatio-temporal Analysis of Multichannel Atrial Electrograms Based on a Concept of Active Areas.
In Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, vol. 2018, pp. 490-493, 2018
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H. Lehrmann, A. Jadidi, J. Minners, J. Chen, B. Müller-Edenborn, R. Weber, O. Dössel, T. Arentz, and A. Loewe.
Novel ECG-criteria For Real-time Assessment Of Anterior Mitral Line Block - “V1-jump” And “V1-delay”.
In Heart Rhythm, vol. 15(5S) , pp. S229, 2018
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A. Loewe, Y. Lutz, A. Fabbri, and S. Severi.
Severe sinus bradycardia due to electrolyte changes as a pathomechanism of sudden cardiac death in chronic kidney disease patients undergoing hemodialysis.
In Heart Rhythm, vol. 15(5S) , pp. S354-S355, 2018
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E. Kovacheva, L. Baron, O. Dössel, and A. Loewe.
Electro-Mechanical Delay in the Human Heart: A Study on a Simple Geometry.
In Computing in Cardiology Conference (CinC), vol. 45, 2018
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A. Daub, A. Loewe, and B. Frohnapfel.
Haemodynamics in an elasto-mechanic model of the human heart.
In Annual Scientific Conference of the International Association of Applied Mathematics and Mechanics, 2018
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L. A. Unger, T. G. Oesterlein, P. Spector, A. Luik, C. Schmitt, A. Loewe, and O. Dössel.
Cycle Length Statistics During Atrial Fibrillation Reflect Refractory Properties of the Underlying Substrate.
In Annual Congress of the European Cardiac Arrhythmia Society, pp. 16-27 A15-61, 2018
S. Severi, A. Fabbri, M. Paci, R. Wilders, Y. Lutz, and A. Loewe.
Computational Modeling of the Cardiac Pacemaking in Humans.
In INdAM Workshop on Mathematical and Numerical Modeling of the Cardiovascular System, 2018
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L. Baron, A. Loewe, and O. Dössel.
From clinics to the virtual beating heart a general modeling workflow for patient-specific electromechanical heart simulations.
In BMTMedPhys 2017, vol. 62(S1) , pp. S70, 2017
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O. Dössel, G. Lenis, A. Loewe, S. Pollnow, M. Rottmann, B. Verma, C. Schmitt, A. Luik, and T. Oesterlein.
Atrial Signals Modeling Meets Biosignal Analysis.
In IFMBE Proceedings, vol. 65, pp. 723-726, 2017
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A. Loewe, S. Debatin, G. Lenis, and O. Dössel.
Optimal ECG lead systems to maximimze left atrial information content.
In BMTMedPhys 2017, vol. 62(s1 - V73) , pp. 68, 2017
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Y. Lutz, . Fabbri A., S. Severi, O. Dössel, and A. Loewe.
Plasma electrolyte concentrations in patients with chronic kidney disease influence cardiac pacemaking in a computational model.
In BMTMedPhys 2017, vol. 62(s1 - V71) , pp. 67, 2017
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T. Oesterlein, A. Loewe, G. Lenis, and O. Dössel.
Statistical assessment of cardiac excitation by morphology-based clustering of local activation waves.
In BMTMedPhys 2017, vol. 62(S1) , pp. S120, 2017
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S. Schuler, L. Baron, A. Loewe, and O. Dössel.
Developing and coupling a lumped element model of the closed loop human vascular system to a model of cardiac mechanics.
In BMTMedPhys 2017, vol. 62(S1) , pp. S69, 2017
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L. Unger, T. Oesterlein, O. Dössel, G. Seemann, P. Spector, and A. Loewe.
Estimating refractory periods during atrial fibrillation based on electrogram cycle lengths in a heterogeneous simulation setup.
In Current Directions in Biomedical Engineering, vol. 3(2) , pp. 317-320, 2017
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A. Loewe, E. Poremba, T. G. Oesterlein, N. Pilia, M. Pfeiffer, O. Doessel, and S. Speidel.
An Interactive Virtual Reality Environment for Analysis of Clinical Atrial Arrhythmias and Ablation Planning.
In 2017 Computing in Cardiology Conference (CinC), vol. 44, 2017
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A. Loewe, S. Debatin, G. Lenis, and O. Dössel.
Maximization of left atrial information through the optimization of ECG lead systems.
2017
  PDF      
N. Pilia, O. Dössel, G. Lenis, and A. Loewe.
ECG as a Tool to Estimate Potassium and Calcium Concentrations in the Extracellular Space.
In Computing in Cardiology, vol. 44, 2017
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A. Fabbri, A. Loewe, R. Wilders, and S. Severi.
Propagation of the primary pacemaker activity in the human heart: a computational approach.
In European Medical and Biological Engineering Conference (EMBEC), vol. 65, pp. 201, 2017
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A. Fabbri, A. Loewe, R. Wilders, and S. Severi.
Pace-and-Drive of the Human Sinoatrial Node – A Preliminary Computational Investigation.
In Computing in Cardiology, vol. 44, 2017
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M. Valinoti, F. Bertoni, M. Alessandrini, R. Mantovan, A. Loewe, O. Dössel, S. Severi, and C. Corsi.
Phase Analysis of Endoatrial Electrograms for 3D Rotor Detection in Atrial Fibrillation.
In Computing in Cardiology Conference, vol. 44, 2017
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M. Alessandrini, M. Valinoti, A. Loewe, T. Oesterlein, O. Dössel, C. Corsi, and S. Severi.
A Computational Framework to Benchmark Basket Catheter Guided Ablation.
In Computing in Cardiology, vol. 44, 2017
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G. Seemann, A. Loewe, and E. M. Wülfers.
Effects of Fibroblasts Coupling on the Electrophysiology of Cardiomyocytes from Different Regions of the Human Atrium: A Simulation Study.
In Computing in Cardiology, vol. 44, 2017
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N. Nagy, A. Loewe, Z. Kohaida, K. Halász, N. Tóth, J. Levijoki, P. Pollesello, T. Koskelainen, L. Otsomaa, A. Tóth, J. Gy, and A. Varró.
Selective Inhibition of the Cardiac Na+/Ca2+ Exchanger by a Novel Compound ORM-10962 Modulates Spontaneous Automaticity.
In European Working Group on Cardiac Cellular Electrophysiology, 2017
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A. Loewe, Y. Lutz, A. Fabbri, S. Severi, G. Seemann, and D. Dössel.
Influence of Electrolyte Concentration Changes on Sinus Node Function - A new Player Regarding Sudden Cardiac Death in Patients with Chronic Kidney Disease?.
In Gordon Research Conference on Cardiac Arrhythmia Mechanisms, 2017
E. M. Wülfers, A. Loewe, and G. Seemann.
A Computational Study on the Electrophysiological Effects of Fibroblasts Coupling to Human Atrial Myocytes from Different Regions.
In Cardiac Physiome Project, 2017
G. Seemann, A. Loewe, and E. M. Wülfers.
Computational Study on Regional Differences in Pro-Arrhythmic Effects of Fibroblasts Coupling to Human Atrial Myocytes.
In TRM Forum, 2017
O. Dössel, and A. Loewe.
V 10 Computer Modelling pharmakologischer Effekte.
In Frühjahrstagung der Deutschen Gesellschaft für Kardiologie, 2017
A. Loewe, R. Andlauer, S. Pollnow, J. Greiner, T. G. Oesterlein, O. Dössel, and G. Seemann.
Validation upside down - In-silico models to sound the potential and limitations of diagnostic tools.
In TRM Forum, 2017
R. Andlauer, A. Loewe, O. Dössel, and G. Seemann.
Effect of left atrial hypertrophy on P-wave morphology in a computational model.
In Current Directions in Biomedical Engineering, vol. 2(1) , pp. 603-606, 2016
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A. Loewe, R. Andlauer, P. G. Platonov, O. Dössel, and G. Seemann.
Left Atrial Hypertrophy Increases P-Wave Terminal Force Through Amplitude but not Duration.
In Computing in Cardiology, vol. 43, pp. 1-4, 2016
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A. Loewe, M. W. Krueger, F. Holmqvist, O. Dössel, G. Seemann, and P. G. Platonov.
P-Wave Terminal Force Is Affected by the Site of Earliest Right Atrial Activation and its Proximity to Inter-Atrial Connections Independent from Atrial Size.
In Biomedizinische Technik, vol. 61, pp. S223, 2016
    
A. Loewe, M. W. Krueger, F. Holmqvist, O. Dössel, G. Seemann, and P. G. Platonov.
P-wave terminal force is affected by site of earliest right atrial activation.
In Cardiac Physiome Project, 2016
A. Loewe, M. W. Krueger, F. Holmqvist, O. Dössel, G. Seemann, and P. G. Platonov.
P-wave terminal force is affected by the site of earliest right atrial activation independent from atrial size in silico.
In International Conference on Electrocardiology, 2016
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B. Verma, A. Loewe, A. Luik, C. Schmitt, and O. Dössel.
Regional Conduction Velocity Calculation based on Local Activation Times: A Simulation Study on Clinical Geometries.
In Computing in Cardiology, vol. 43, pp. 985-988, 2016
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E. Shin, E. Poremba, O. Dössel, and A. Loewe.
Automated Initiation of Fibrillatory Excitation in Monodomain Simulations.
2016
A. Loewe, M. W. Krueger, P. G. Platonov, F. Holmqvist, O. Dössel, and G. Seemann.
P-wave morphology is affected by site of earliest right atrial activation: a simulation study.
In TRM Forum, 2015
A. Loewe, Y. Lutz, M. Wilhelms, D. Sinnecker, P. Barthel, E. P. Scholz, O. Dössel, G. Schmidt, and G. Seemann.
In-silico Assessment of the Dynamic Effects of Amiodarone and Dronedarone on Human Atrial Patho-Electrophysiology.
In Cardiac Physiome Workshop, 2015
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A. Loewe, Y. Xu, E. P. Scholz, O. Dössel, and G. Seemann.
Understanding the cellular mode of action of vernakalant using a computational model: answers and new questions.
In Current Directions in Biomedical Engineering, vol. 1(1) , pp. 418–-422, 2015
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N. A. Pilia, G. Lenis, A. Loewe, W. H. W. Schulze, and . O. Dössel.
The impact of baseline wander removal techniques on the ST segment in simulated ischemic 12-lead ECG.
In Current Directions in Biomedical Engineering, vol. 1(1) , pp. 96-99, 2015
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J. Trächtler, T. Oesterlein, A. Loewe, E. Poremba, A. Luik, C. Schmitt, and O. Dössel.
Virtualizing clinical cases of atrial flutter in a fast marching simulation including conduction velocity and ablation scars.
In Current Directions in Biomedical Engineering, vol. 1(1) , pp. 405-408, 2015
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A. Loewe, M. W. Krueger, P. G. Platonov, F. Holmqvist, O. Dössel, and G. Seemann.
Left and Right Atrial Contribution to the P-wave in Realistic Computational Models.
In Lecture Notes in Computer Science, vol. 9126, pp. 439–447, 2015
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M. Rottmann, L. Unger, W. Kaltenbacher, G. Seemann, A. Loewe, M. W. Krueger, A. S. Jadidi, T. Arentz, and O. Doessel.
Methods for analyzing signal characteristics of stable and unstable rotors in a realistic heart model.
In 2015 Computing in Cardiology Conference (CinC), pp. 485-488, 2015
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A. Loewe, Y. Lutz, M. Wilhelms, D. Sinnecker, P. Barthel, E. P. Scholz, O. Dössel, G. Schmidt, and G. Seeman.
In-silico Assessment of the Dynamic Effects of Amiodarone and Dronedarone on Human Atrial Patho-Electrophysiology.
In Atrial Signals, 2015
A. Loewe, M. Wilhelms, Y. Lutz, O. Dössel, and G. Seemann.
In-silico Assessment of the Dynamic Effects of Amiodarone and Dronedarone on Human Atrial Patho-Electrophysiology.
In Emerging Mathematical Topics in Biology and Life Sciences, 2015
A. Loewe, Y. Lutz, M. Wilhelms, E. P. Scholz, O. Dössel, and G. Seemann.
Optimization of pharmacotherapy for familial atrial fibrillation in a numerical model of human atrial electrophysiology.
In Computing in Cardiology, vol. 41, pp. 745-748, 2014
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A. Loewe, M. Wilhelms, O. Dössel, and G. Seemann.
Influence of chronic atrial fibrillation induced remodeling in a computational electrophysiological model.
In Biomedizinische Technik / Biomedical Engineering, vol. 59(S1) , pp. S929-S932, 2014
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Y. Lutz, A. Loewe, O. Dössel, and G. Seemann.
Specific antiarrhythmic therapy for familial atrial fibrillation in a numerical model of human atrial electrophysiology.
In Biomedizinische Technik / Biomedical Engineering, vol. 59(s1) , pp. s933-s936, 2014
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A. Loewe, M. Wilhelms, Y. Lutz, O. Dössel, and G. Seemann.
Modeling human atrial patho-electrophysiology: genetic defects and pharmacological agents.
In Simula Cardiac Modeling Workshop, 2014
J. Liu, A. Loewe, M. Zenge, A. Lefebvre, E. Mueller, and M. S. Nadar.
Elora: Enforcing Low Rank for Parallel MR Reconstruction.
In International Society for Magnetic Resonance in Medicine, pp. 2652, 2013
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A. Loewe, E. Poremba, M. W. Krueger, O. Dössel, and G. Seemann.
Fast Marching Simulation of Atrial Excitation: Towards Personalized Ablation Planning.
In TRM Forum, 2013
A. Loewe, M. Wilhelms, F. Fischer, E. P. Scholz, O. Dössel, and G. Seemann.
Impact of hERG Mutations on Simulated Human Atrial Action Potentials.
In Biomedizinische Technik/Biomedical Engineering, vol. 58(s1) , 2013
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A. Loewe, M. Wilhelms, J. Schmid, M. J. Krause, F. Fischer, E. P. Scholz, O. Dössel, and G. Seemann.
A Hybrid Optimization Approach for the Adaptation of Cardiac Ion Current Formulations to Voltage and Patch Clamp Data.
In Cardiac Physiome Workshop, 2013
W. H. W. Schulze, F. Elies Henar, D. Potyagaylo, A. Loewe, M. Stenroos, and O. Dössel.
Kalman Filter with Augmented Measurement Model: an ECG Imaging Simulation Study.
In FIMH, LNCS 7945, pp. 200-207, 2013
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O. Dössel, G. Seemann, A. Loewe, Y. Lutz, and M. Wilhelms.
Simulating the Effects of Drugs and Genetic Defects on Atrial Electrophysiology.
In TRM Forum, 2013
A. Loewe, W. H. W. Schulze, Y. Jiang, M. Wilhelms, and O. Dössel.
Determination of optimal electrode positions of a wearable ECG monitoring system for detection of myocardial ischemia: a simulation study.
In Computing in Cardiology, vol. 38, pp. 741-744, 2011
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Patents (2)

A. Lefebvre, A. Loewe, M. S. Nadar, and J. Liu.
Zero communication block partitioning.
2014.
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J. Liu, Z. Yang, M. S. Nadar, N. Janardhanan, Q. Wang, and A. Loewe.
Multi-stage Magnetic Resonance Reconstruction for Parallel Imaging Applications.
2014.
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Dissertations (2)

A. Loewe.
Simulation of Cardiac Electrophysiology and Biomechanics: from Model Development to Clinical Translation.
Karlsruhe Institute of Technology (KIT). Habilitationsschrift. 2021
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A. Loewe.
Modeling human atrial patho-electrophysiology from ion channels to ECG: substrates, pharmacology, vulnerability, and P-waves.
KIT Scientific Publishing. Dissertation. 2016
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Student Theses (2)

A. Loewe.
Arrhythmic potency of human electrophysiological models adapted to chronic and familial atrial fibrillation.
Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT). Masterarbeit. 2013
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A. Loewe.
Comparison of cardiac simulation tools regarding the modeling of acute ischemia.
Institut für Biomedizinische Technik, Karlsruher Institut für Technologie (KIT). Bachelorarbeit. 2010
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