IBT Publications by Wilhelms


Journal Articles (12)

M. Wilhelms, O. Dössel, and G. Seemann.
In silico investigation of electrically silent acute cardiac ischemia in the human ventricles.
In IEEE Transactions on Biomedical Engineering, vol. 58(10) , pp. 2961-2964, 2011
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M. Wilhelms, H. Hettmann, M. M. C. Maleckar, J. T. Koivumäki, O. Dössel, and G. Seemann.
Benchmarking electrophysiological models of human atrial myocytes.
In Frontiers in Physiology, vol. 3(487) , pp. 1-16, 2013
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M. Wilhelms, L. P. Holl, O. Dössel, and G. Seemann.
Impact of antiarrhythmic drugs on a virtual model of atrial fibrillation.
In Biomedizinische Technik / Biomedical Engineering, vol. 57 Suppl 1, 2012
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M. Wilhelms, C. Rombach, E. P. Scholz, O. Doessel, and G. Seemann.
Impact of amiodarone and cisapride on simulated human ventricular electrophysiology and electrocardiograms.
In Europace, vol. 14, pp. v90-v96, 2012
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O. Dössel, M. W. Krueger, F. M. Weber, M. Wilhelms, and G. Seemann.
Computational modeling of the human atrial anatomy and electrophysiology.
In Medical & Biological Engineering & Computing, vol. 50(8) , pp. 773-799, 2012
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M. Keller, S. Schuler, M. Wilhelms, G. Lenis, G. Seemann, C. Schmitt, O. Dössel, and A. Luik.
Characterization of radiofrequency ablation lesion development based on simulated and measured intracardiac electrograms.
In IEEE Transactions on Biomedical Engineering, vol. 61(9) , pp. 2467-2478, 2014
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A. Loewe, Y. Lutz, M. Wilhelms, D. Sinnecker, P. Barthel, E. P. Scholz, O. Dossel, G. Schmidt, and G. Seemann.
In-silico assessment of the dynamic effects of amiodarone and dronedarone on human atrial patho-electrophysiology.
In Europace, vol. 16(suppl 4) , pp. iv30-iv38, 2014
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A. Loewe, W. H. W. Schulze, Y. Jiang, M. Wilhelms, A. Luik, O. Dössel, and G. Seemann.
ECG-Based Detection of Early Myocardial Ischemia in a Computational Model: Impact of Additional Electrodes, Optimal Placement, and a New Feature for ST Deviation.
In BioMed Research International Article, vol. 2015, pp. 530352, 2014
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A. Loewe, M. Wilhelms, F. Fischer, E. P. Scholz, O. Dössel, and G. Seemann.
Arrhythmic potency of human ether-a-go-go-related gene mutations L532P and N588K in a computational model of human atrial myocytes.
In Europace, vol. 16(3) , pp. 435-443, 2014
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A. Loewe, M. Wilhelms, J. Schmid, M. J. Krause, F. Fischer, D. Thomas, E. P. Scholz, O. Dössel, and G. Seemann.
Parameter estimation of ion current formulations requires hybrid optimization approach to be both accurate and reliable.
In Frontiers in Bioengineering and Biotechnology, vol. 3, pp. 209, 2016
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E. P. Scholz, P. Carrillo-Bustamante, F. Fischer, M. Wilhelms, E. Zitron, O. Dössel, H. A. Katus, and G. Seemann.
Rotor termination is critically dependent on kinetic properties of I kur inhibitors in an in silico model of chronic atrial fibrillation.
In PloS one, vol. 8(12) , pp. e83179, 2013
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G. Seemann, D. U. J. Keller, M. W. Krueger, F. M. Weber, M. Wilhelms, and O. Dössel.
Electrophysiological modeling for cardiology: methods and potential applications.
In Information Technology, vol. 52(5) , pp. 242-249, 2010
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Book Chapters (1)

G. Seemann, M. W. Krueger, and M. Wilhelms.
Elektrophysiologische Modellierung und Virtualisierung für die Kardiologie - Methoden und potenzielle Anwendungen.
In Der virtuelle Patient, W. Niederlag, H. Lemke, H. Lehrach (eds), Health Academy, pp. 98-116, 2012
  

Conference Contributions (17)

M. Wilhelms, O. Dössel, and G. Seemann.
Comparing Simulated Electrocardiograms of Different Stages of Acute Cardiac Ischemia.
In FIMH 2011, LNCS, vol. 6666, pp. 11-19, 2011
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M. Wilhelms, O. Dössel, and G. Seemann.
Simulating the Impact of the Transmural Extent of Acute Ischemia on the Electrocardiogram.
In Computing in Cardiology, vol. 37, pp. 13-16, 2010
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M. Wilhelms, J. Schmid, M. J. Krause, N. Konrad, J. Maier, E. P. Scholz, V. Heuveline, O. Dössel, and G. Seemann.
Calibration of human cardiac ion current models to patch clamp measurement data.
In Computing in Cardiology, vol. 39, pp. 229-232, 2012
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M. Wilhelms, G. Seemann, and O. Dössel.
Benchmarking different models describing sinus node heterogeneity.
In IFMBE Proceedings, vol. 22, pp. 2691-2694, 2008
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M. Wilhelms, G. Seemann, M. Weiser, and O. Dössel.
Benchmarking Solvers of the Monodomain Equation in Cardiac Electrophysiological Modeling.
In Biomedizinische Technik / Biomedical Engineering, vol. 55(s1) , pp. 99-102, 2010
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A. Loewe, Y. Lutz, M. Wilhelms, E. P. Scholz, O. Dössel, and G. Seemann.
Optimization of pharmacotherapy for familial atrial fibrillation in a numerical model of human atrial electrophysiology.
In Computing in Cardiology, vol. 41, pp. 745-748, 2014
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A. Loewe, Y. Lutz, M. Wilhelms, D. Sinnecker, P. Barthel, E. P. Scholz, O. Dössel, G. Schmidt, and G. Seeman.
In-silico Assessment of the Dynamic Effects of Amiodarone and Dronedarone on Human Atrial Patho-Electrophysiology.
In Atrial Signals, 2015
A. Loewe, Y. Lutz, M. Wilhelms, D. Sinnecker, P. Barthel, E. P. Scholz, O. Dössel, G. Schmidt, and G. Seemann.
In-silico Assessment of the Dynamic Effects of Amiodarone and Dronedarone on Human Atrial Patho-Electrophysiology.
In Cardiac Physiome Workshop, 2015
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A. Loewe, W. H. W. Schulze, Y. Jiang, M. Wilhelms, and O. Dössel.
Determination of optimal electrode positions of a wearable ECG monitoring system for detection of myocardial ischemia: a simulation study.
In Computing in Cardiology, vol. 38, pp. 741-744, 2011
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A. Loewe, M. Wilhelms, O. Dössel, and G. Seemann.
Influence of chronic atrial fibrillation induced remodeling in a computational electrophysiological model.
In Biomedizinische Technik / Biomedical Engineering, vol. 59(S1) , pp. S929-S932, 2014
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A. Loewe, M. Wilhelms, F. Fischer, E. P. Scholz, O. Dössel, and G. Seemann.
Impact of hERG Mutations on Simulated Human Atrial Action Potentials.
In Biomedizinische Technik/Biomedical Engineering, vol. 58(s1) , 2013
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A. Loewe, M. Wilhelms, Y. Lutz, O. Dössel, and G. Seemann.
Modeling human atrial patho-electrophysiology: genetic defects and pharmacological agents.
In Simula Cardiac Modeling Workshop, 2014
A. Loewe, M. Wilhelms, Y. Lutz, O. Dössel, and G. Seemann.
In-silico Assessment of the Dynamic Effects of Amiodarone and Dronedarone on Human Atrial Patho-Electrophysiology.
In Emerging Mathematical Topics in Biology and Life Sciences, 2015
A. Loewe, M. Wilhelms, J. Schmid, M. J. Krause, F. Fischer, E. P. Scholz, O. Dössel, and G. Seemann.
A Hybrid Optimization Approach for the Adaptation of Cardiac Ion Current Formulations to Voltage and Patch Clamp Data.
In Cardiac Physiome Workshop, 2013
G. Seemann, M. Alvarez de Eulate, N. Konrad, J. Maier, M. Wilhelms, D. Keller, O. Dössel, and E. Scholz.
Evaluating body surface ECG differences of simulated long-QT syndromes.
2013
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G. Seemann, P. Carrillo Bustamante, S. Ponto, M. Wilhelms, E. P. Scholz, and O. Dössel.
Atrial fibrillation-based electrical remodeling in a computer model of the human atrium.
In Proc. Computing in Cardiology, vol. 37, pp. 417-420, 2010
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G. Seemann, A. Loewe, Y. Lutz, M. Wilhelms, and O. Dössel.
Simulating the Effects of Drugs and Genetic Defects on Atrial Electrophysiology.
In TRM Forum, 2013

Dissertations (1)

M. Wilhelms.
Multiscale Modeling of Cardiac Electrophysiology: Adaptation to Atrial and Ventricular Rhythm Disorders and Pharmacological Treatment.
KIT Scientific Publishing. Dissertation. 2013
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Student Theses (1)

M. Wilhelms.
Analysis of cardiac ischemia regarding ECG and stability in a computer model of the human ventricles.
Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT). Diplomarbeit. 2009
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